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. 2018 Nov 28;19(1):1. doi: 10.1007/s10158-018-0221-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — A diagram to summarize a putative intracellular mechanism for a peptide-mediated reduction of neuron sensitivity to a chemical transmitter, for example, acetylcholine. P-R, peptide receptor; G-prot, G-protein; cADPR, cyclic adenosine diphosphate-ribose; ATP, adenosine triphosphate; IP₃, inositol-1,4,5-triphosphate; RY-R, ryanodine receptor; IP₃-R, IP₃ receptor; ACh-R, acetylcholine receptor; activation/increase of intracellular level, white/blue/orange arrow; inhibition of intracellular level, black arrow

Modified from Pivovarov et al. (2007)