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. 2018 Oct 4;38(12):1189–1196. doi: 10.1007/s40261-018-0710-9
Baloxavir marboxil was well tolerated and had a generally favorable safety profile up to an 80 mg single oral dose.
The pharmacokinetic profile showing a long half-life supports a single oral dose.
The exposure of baloxavir acid decreased under the fed state.