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. 2018 Apr 6;57(12):1571–1580. doi: 10.1007/s40262-018-0649-2
Renal impairment did not appear to impact the pharmacokinetic properties of oral semaglutide following ten consecutive once-daily doses.
Oral semaglutide was well-tolerated in subjects with varying degrees of renal impairment.
These data suggest that renal impairment should not affect the dosing recommendations of oral semaglutide.