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. 2018 Nov 13;9(89):35875–35890. doi: 10.18632/oncotarget.26251

1b. Top 20 GO term associated with significantly up regulated kinases after searching in DAVID database.

SL# GO ID Term Count P-Value Genes (Uniprot Accession)
1 GO:0018108 peptidyl-tyrosine phosphorylation 7 5.91E-09 P54762, P07332, P09619, P06241, P17948, Q15303, Q15375
2 GO:0000165 MAPK cascade 6 4.72E-06 P09619, P06241, P27361, P53778, Q13164, Q15303
3 GO:0007165 signal transduction 6 0.00480611 P06401, P09619, P11802, P53778, Q13164, Q15303
4 GO:0006351 transcription, DNA-templated 6 0.0397312 P06401, Q08999, Q14765, P27361, P53778, Q15303
5 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 5 4.69E-07 P09619, P22681, P06241, P17948, Q15303
6 GO:0046777 protein autophosphorylation 5 2.28E-05 P54762, P07332, P09619, P17948, Q15303
7 GO:0038083 peptidyl-tyrosine autophosphorylation 4 8.32E-06 P07332, P06241, P27361, Q15303
8 GO:0048010 vascular endothelial growth factor receptor signaling pathway 4 4.92E-05 P06241, P53778, P17948, P46108
9 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 4 6.26E-05 P09619, P06241, P27361, Q15303
10 GO:0048013 ephrin receptor signaling pathway 4 8.37E-05 P54762, P06241, Q15375, P46108
11 GO:0001934 positive regulation of protein phosphorylation 4 2.66E-04 P07355, P27361, Q15303, Q15375
12 GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 4 2.66E-04 P20963, P06241, P27361, P46108
13 GO:0016477 cell migration 4 6.46E-04 P09619, P06241, P17948, Q15303
14 GO:0043066 negative regulation of apoptotic process 4 0.01012794 P09619, P22681, Q13164, Q15303
15 GO:0006468 protein phosphorylation 4 0.01018863 P07332, P11802, P06241, P27361
16 GO:0008284 positive regulation of cell proliferation 4 0.01080736 P09619, P11802, P17948, Q15303
17 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 4 0.0732784 P06401, Q14765, P27361, Q13164
18 GO:0036120 cellular response to platelet-derived growth factor stimulus 3 1.46E-04 P09619, P22681, P06241
19 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 3 4.41E-04 P09619, P17948, Q15303
20 GO:0048146 positive regulation of fibroblast proliferation 3 0.0013384 P07355, P09619, P11802