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. 2018 Nov 13;9(89):35997–36011. doi: 10.18632/oncotarget.26323

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Copyright: © 2018 Ueda et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Kaplan–Meier survival curves of 16 patients with refractory esophageal or head/neck squamous cell carcinoma who were vaccinated with CHP-MAGE-A4. Six patients were given a 100 μg vaccine dose, while the other 10 patients were given the 300 μg dose. The survival times are not statistically different (p = 0.1320). (B) 15 patients with refractory esophageal or head/neck squamous cell carcinoma, were evaluated for the immune responses to MAGE-A4. Patient No. 10 (code No. 704) was excluded, in whom the antibody datum at post-vaccine was not available. Four patients with esophageal or head/neck squamous carcinoma exhibited immune responses to MAGE-A4. The other 11 patients did not have such responses. The survival times are not statistically different (p = 0.2165).

(A) Kaplan–Meier survival curves of 16 patients with refractory esophageal or head/neck squamous cell carcinoma who were vaccinated with CHP-MAGE-A4. Six patients were given a 100 μg vaccine dose, while the other 10 patients were given the 300 μg dose. The survival times are not statistically different (p = 0.1320). (B) 15 patients with refractory esophageal or head/neck squamous cell carcinoma, were evaluated for the immune responses to MAGE-A4. Patient No. 10 (code No. 704) was excluded, in whom the antibody datum at post-vaccine was not available. Four patients with esophageal or head/neck squamous carcinoma exhibited immune responses to MAGE-A4. The other 11 patients did not have such responses. The survival times are not statistically different (p = 0.2165).