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. 2018 Nov 27;11:8399–8408. doi: 10.2147/OTT.S182573

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© 2018 Ma et al. This work is published and licensed by Dove Medical Press Limited

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ANCR knockdown inhibits NPC cell growth and radiation resistance.

Notes: (A, B) Relative mRNA level of ANCR was detected in transfected SUNE-1 and HONE-1 cell lines. (C, D) Cell viability was measured by CCK-8 assay. (E) Cell clone formation ability was detected by colony formation assay. (F, G) Colony formation assay was also used to measure colony survival rate 2 weeks after transfected SUNE-1 and HONE-1 cell lines being exposed to the indicated single doses of irradiation (0, 2, 4, 6, or 8 Gy). Data were mean±SD of three independent experiments; Student’s t-test, *P<0.05 compared with indicated controls.

Abbreviations: ANCR, antidifferentiation noncoding RNA; CCK-8, cell counting kit-8; NPC, nasopharyngeal carcinoma.