Table 2.
Univariable HRs and corresponding 95% CIs for overall mortality by gender
| Exposure | Women HR (95% CI) | Men HR (95% CI) |
|---|---|---|
| BI | ||
| 80–100 | 1 (reference) | 1 (reference) |
| 50–79 | 1.42 (1.38–1.47) | 1.40 (1.35–1.46) |
| 25–49 | 1.76 (1.70–1.82) | 1.73 (1.66–1.81) |
| 0–24 | 2.72 (2.62–2.82) | 2.29 (2.19–2.39) |
| Age group (years) | ||
| 65–74 | 1 (reference) | 1 (reference) |
| 75–84 | 1.38 (1.33–1.44) | 1.51 (1.45–1.57) |
| 85–94 | 2.07 (1.99–2.16) | 2.26 (2.17–2.35) |
| ≥95 | 3.30 (3.12–3.50) | 3.25 (2.98–3.55) |
| Period of admission | ||
| 2005–2009 | 1 (reference) | 1 (reference) |
| 2010–2014 | 1.02 (0.99–1.04) | 1.01 (0.99–1.04) |
| CCIa | ||
| 0 | 1 (reference) | 1 (reference) |
| 1–2 | 1.44 (1.39–1.49) | 1.28 (1.21–1.35) |
| ≥3 | 2.14 (2.06–2.21) | 1.86 (1.76–1.96) |
| Medications at admissionb | ||
| 0 | 1 (reference) | 1 (reference) |
| 1–4 | 1.08 (1.01–1.15) | 1.21 (1.13–1.30) |
| 5–9 | 1.25 (1.18–1.34) | 1.44 (1.34–1.54) |
| ≥10 | 1.39 (1.29–1.50) | 1.60 (1.47–1.74) |
| Prior (1 year) hospital admissionc | ||
| 0 | 1 (reference) | 1 (reference) |
| 1–2 | 1.15 (1.12–1.17) | 1.17 (1.14–1.21) |
| ≥3 | 1.34 (1.29–1.39) | 1.49 (1.43–1.55) |
Notes:
a
The CCI was calculated based on hospital discharge diagnoses during 10 years before baseline.
b
All redeemed prescriptions were included, except from the following ATC codes: B05x (blood substitutes and perfusion solutions), B06x (other hematological agents), D09x (medicated dressings), J07x (vaccines), N01x (anesthetics), and Vx (various); medications were counted at the fourth level of the ATC code, ie, including the first five digits of the ATC code (eg, salicylic acid and derivates: N02BA).
c
Based on hospital admissions during 1 year before baseline.
Abbreviations: ATC, Anatomical Therapeutic Chemical; BI, Barthel Index; CCI, Charlson comorbidity index.