Table 3.
Airway dimension measurements and correlations to clinical indices
| Measured value | Correlation to FEV1/FVC | Correlation to FEV1 predicted | Correlation to smoking index | |
|---|---|---|---|---|
|
| ||||
| Mean±SD (range) | r (P-value) | r (P-value) | r (P-value) | |
|
| ||||
| Nondependent main bronchus | ||||
| End-inspiratory Ai (mm2) | 148.6±51.4 (73.3–302.7) | 0.004 (0.98) | −0.031 (0.847) | 0.047 (0.769) |
| End-expiratory Ai (mm2) | 125.6±44.5 (57.5–237.6) | 0.102 (0.52) | 0.096 (0.547) | −0.006 (0.970) |
| ΔAi EI (%) | 10.5±10.6 ([−13.7]–38.5) | −0.431 (0.004a) | −0.300 (0.054) | 0.041 (0.797) |
| ΔAi1.05 (%) | 6.8±7.9 ([−7.0]–30.0) | −0.465 (0.002a) | −0.290 (0.063) | 0.099 (0.535) |
| Dependent main bronchus | ||||
| End-inspiratory Ai (mm2) | 132.3±45.1 (66.9–273.3) | −0.050 (0.755) | −0.078 (0.623) | 0.310 (0.046a) |
| End-expiratory Ai (mm2) | 105.2±31.8 (41.5–166.9) | 0.037 (0.817) | 0.062 (0.698) | 0.192 (0.224) |
| ΔAi EI (%) | 18.5±10.9 ([−8.5]–44.4) | −0.232 (0.140) | −0.276 (0.077) | 0.256 (0.102) |
| ΔAi1.05 (%) | 14.1±10.5 (1.9–44.9) | −0.311 (0.045a) | −0.523 (<0.001a) | 0.291 (0.062) |
Note:
a
Significant.
Abbreviations: Ai, luminal area; ΔAiEI, the subtracted value of the peak expiratory Ai from the peak inspiratory Ai divided by the peak inspiratory Ai; ΔAi1.05, the subtracted value of the Ai at the third frame (1.05 seconds) after the peak inspiration divided by the peak inspiratory Ai.