Table 4.

List of the significantly interacting SNP in the WTCCC RA data [7, 9, 34–40]

The 31 2-SNP interactions found significant by at least 4 methods. The corresponding SNP names and positions are also reported. Ref 1 and Ref 2 (when any) refer to previous studies where the corresponding SNP were already reported. Gene 1 and Gene 2 (when any) are reported when the corresponding SNP are located in a gene (in intronic, exonic or UTR regions). The methods for which the SNP were reported as significant are indicated by a colored cell. Furthermore, 3 rankings are also reported: the first one is the one used to rank the interactions in the Table and is described in the text. The second is the balanced accuracy computed by KNN-MDR. The third one is the rank of the average rank of the interaction computed over the methods for which this interaction was significant