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. 2018 Nov 29;14:374. doi: 10.1186/s12917-018-1698-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Sigmoid maximum effect (E_max) relationship between the in vivo antimicrobial effect against E. coli O78 in three tissues of chicken and the area under the concentration-time curve from 0 to 24 h (AUC_0–24)/minimum inhibitory concentration (MIC) ratio of enrofloxacin and ciprofloxacin. [enrofloxacin (ENR); ciprofloxacin (CIP)]