Table 3.
Association between serum TCDD levels and infertility based on 285 women who tried to become pregnant after the explosion, Seveso Women’s Health Study, Italy, 1996–1998.
| Crude | Adjusted* | ||
|---|---|---|---|
| Infertile/Total | OR (95% CI) | OR (95% CI) | |
| Serum TCDD (ppt) | |||
| Continuous | |||
| log10 TCDD | 49/285 | 1.78 (1.10, 2.90) | 1.92 (1.14, 3.22) |
| Categorical | |||
| ≤20 | 6/53 | 1.00 | 1.00 |
| 20.1–44.4 | 9/76 | 1.05 (0.35, 3.16) | 1.14 (0.36, 3.64) |
| 44.5–100 | 16/78 | 2.02 (0.73, 5.56) | 2.45 (0.83, 7.25) |
| >100 | 18/78 | 2.35 (0.86, 6.39) | 2.77 (0.95, 8.10) |
| Extrapolated TCDD (ppt) | |||
| Continuous | |||
| log10 TCDD | 49/285 | 1.85 (1.14, 2.99) | 2.04 (1.22, 3.41) |
| Quartiles | |||
| <6.0 | 9/70 | 1.00 | 1.00 |
| 6.0–14.2 | 10/74 | 1.06 (0.40, 2.78) | 1.28 (0.46, 3.52) |
| 14.3–40.7 | 12/71 | 1.38 (0.54, 3.51) | 1.81 (0.66, 4.96) |
| >40.7 | 18/70 | 2.35 (0.97, 5.66) | 2.80 (1.09, 7.18) |
*
Adjusted for parity, maternal and paternal age, irregular menstrual cycle, oral contraceptive use in past year, smoking, and history of gynecological or chronic health condition.