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. 2018 Nov 29;18:1193. doi: 10.1186/s12885-018-5122-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Experimental design. Experimental protocol design for (a) the detection and description of osteosarcoma in two different experimental orthotopic models using [¹⁸F]FDG and Na[¹⁸F]F radiotracers and (b) the assessment of a new experimental treatment based on the use of the oncolytic adenovirus VCN-01by [¹⁸F]FDG. “n” refers the number of tumors analyzed