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. 2018 Nov 29;18:1193. doi: 10.1186/s12885-018-5122-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Tumor detection by [¹⁸F]FDG and Na[¹⁸F]F. Gross examination of osteosarcoma tumors developed in mice with the 531MII cell line (a) and PET images obtained with [¹⁸F]FDG (b) or Na[¹⁸F]F (c). Images on the left and on the right side of the figure correspond to two different animals (case 1 and case 2). PET with [¹⁸F]FDG clearly distinguished the presence or absence of tumors (red arrows). On the other hand, Na[¹⁸F]F failed to reveal some tumors. Red positive sign: true positive; green negative sign: true negative; yellow asterisk: false negative