Table 1.
Representative top molecules identified by IPA analysis after CEPO treatment
| Gene Symbol | Fold Change |
Genebank Accn |
Description | Molecular Function |
|---|---|---|---|---|
|
Up-regulated genes |
||||
| Ddx3x | 14.599 | NM_ 0011082 46 | DEAD-box helicase 3, X-linked | Helicase |
| KAT2B | 12.401 | XM_ 0037506 17 | lysine acetyltransferase 2B | Transcription regulator |
| CIRBP | 10.999 | NM_031147 | cold inducible RNA binding protein | Translation regulator |
| CHRDL1 | 10.636 | NM_199502 | chordin like 1 | plays a role in neuronal differentiation |
| POGZ | 10.337 | NM_ 0011076 93 | pogo transposable element derived w ith ZNF domain | transposase |
| ALY REF | 9.963 | NM_ 0011096 02 | Aly/REF export factor | Transcription regulator |
| Cts8 | 9.288 | NM_ 0011282 16 | cathepsin 8 | Peptidase |
| ELAC1 | 9.193 | NM_ 0011074 06 | elaC ribonuclease Z 1 | ribonuclease |
| PPP1R3A | 9.023 | NM_ 0011092 22 | protein phosphatase 1 regulatory subunit 3A | Phosphatase |
| PAQR7 | 8.931 | NM_ 0010340 81 | progestin and adipoQ receptor family member 7 | Steroid membrane receptor |
|
Down-regulated genes |
||||
| CHMP4B* | −6.315 | NM_0012764 56 |
charged multivesicular body protein 4B | protein homodimerization activity |
| NPM3 | −4.762 | XM_0010585 48 | nucleophosmin/nucleoplasmin 3 | chaperone protein |
| GABRA5 | −3.948 | NM_017295 | gamma-aminobutyric acid type A receptor alpha5 subunit | Ion Channel |
| Raet11 | −3.785 | NM_0010130 63 | retinoic acid early transcript 1L | Peptide antigen binding |
| KLK1* | −3.73 | NM_0010053 82 | kallikrein 1 | Peptidase |
| GJD2 | −3.517 | NM_019281 | gap junction protein delta 2 | Transporter |
| SNW1 | −3.497 | NM_0011092 79 | SNW domain containing 1 | Transcription regulator |
| KIF1C | −3.353 | NM_145877 | kinesin family member 1C | microtubule motor activity |
| GZMB | −3.294 | NM_138517 | granzyme B | Peptidase |
| Olr1124 | −3.127 | NM 0010004 26 | olfactory receptor 1124 | G-protein coupled receptor |
Table shows top 10 upregulated and downregulated molecules with their gene symbol, fold change value, gene bank accession number, description and molecular function.