Table 1. Distribution of virulence related genes of chromosomal (SPIs, Non-SPI) and extrachromosomal origin (plasmids) among local isolates of S. Typhi (in percent).
| Location | Virulence Related Genes |
Percentage of S. Typhi Strains Positive by PCR | |
|---|---|---|---|
| Vi-positive n = 31 |
Vi-negative n = 4 |
||
| SPI-1 | invA, prgI, hilA, sipA, prgH | 100 | 100 |
| SPI-2 | spiC, sseB | 100 | 100 |
| SPI-3 | mgtb, mgtC, nepI/gaiA | 100 | 100 |
| SPI-4 | spi4d, orfL | 100 | 100 |
| SPI-5 | pipB, pipD, sopB/sigD | 100 | 100 |
| SPI-6 | tcf, safC | 100 | 100 |
| SPI-7 | pilS, tviA, tviB, tviD-E | 100 | 0 |
| SPI-7 | sopE | 100 | 100 |
| SPI-8 | STY3280, STY3282 | 100 | 100 |
| SPI-9 | prtB, STY-2875 | 100 | 100 |
| SPI-10 | sefC, sefB, sefR, prpZ, prkY, prkX | 100 | 0 |
| SPI-11 | pagC, pagD, msgA, cdtB | 100 | 100 |
| SPI-12 | sspH2 | 100 | 100 |
| SPI-16 | gtrA, gtrB | 100 | 100 |
| SPI-17 | STY-2629 | 100 | 100 |
| SPI-18 | clyA/sheA/hlyE, taiA | 100 | 100 |
| Non-SPI | agfA, stgA, fimA, staA, sifA, phoP, rpoS, fliA, tolC, STY1460 | 100 | 100 |
| *R27, *pHCM1 | trhW | 29 | 0 |
| *pRST98 | spvB, spvR | 0 | 0 |
*Plasmids