Table 1.

ED₅₀ Values (μg/mL) of Extract, Fractions, and Active Compounds Isolated from B. fagaroides var. fagaroides against four human cancer cell lines.

Compound	KB	PC-3	MCF-7	HF-6
HA	9.6 × 10−2 ± 0.07	2.5 × 10−1 ± 0.03	6.6 ± 0.01	7.1 × 10−3 ± 0.1
F-1	6.0 × 10−3 ± 0.08	1.0 × 10−5 ± 0.006	8.8 × 10−1 ± 0.03	4.3 × 10−3 ± 0.04
F-2	1.3 × 10−1 ± 0.02	1.0 × 10−5 ± 0.004	8.2 × 10−1 ± 0.03	3.6 × 10−2 ± 0.02
F-1-1	3.94 × 10−1 ± 0.08	1.0 × 10−5 ± 0.1	8.1 ± 0.1	8.0 × 10−5 ± 0.03
F-1-2	3.5 × 10−1 ± 0.02	7.8 × 10−4 ± 0.06	1.3 ± 0.08	6.5 × 10−3 ± 0.01
F-2-1	1.9 × 10−1 ± 0.01	4.2 × 10−3 ± 0.02	>20	3.5 × 10−2 ± 0.02
F-2-2	3.2 ± 0.01	2.0 ± 0.1	>20	2.9 ± 0.05
F-2-3	1.0 × 10−2 ± 0.01	5.5 × 10−3 ± 0.01	2.5 × 10−7 ± 0.03	2.6 × 10−3 ± 0.001
1	1.91 × 10−6 ± 0.01	0.95 ± 0.005	1.04 × 10−5 ± 0.031	1.8 × 10−4 ± 0.01
2	0.189 ± 0.01	0.085 ± 0.005	0.798 ± 0.01	3.8 × 10−2 ± 0.01
3	1.0 × 10−5 ± 0.02	1.0 × 10−5 ± 0.004	1.02 × 10−4 ± 0.005	0.40 ± 0.01
4	0.4 ± 0.03	1.7 × 10−3 ± 0.01	0.4 ± 0.01	0.68 ± 0.01
5	1.5 ± 0.01	2.0 × 10−3 ± 0.003	1.25 ± 0.01	1.23 ± 0.01
6	2.89 ± 0.009	2.0 × 10−3 ± 0.005	3.68 ± 0.08	2.89 ± 0.006
7	1.03 ± 0.01	5.0 × 10−3 ± 0.005	>4	2.41 ± 0.004
Camptothecin	1.58 × 10−3 ± 0.01	0.96 ± 0.006	1.28 × 10−4 ± 0.01	5.5 × 10−6 ± 0.01
Podophyllotoxin	8.7 × 10−5 ± 0.003	0.85 ± 0.009	9.9 × 10−5 ± 0.005	7.6 × 10−3 ± 0.05
Etoposide	25 × 10−3 ± 0.002	5.6 × 10−3 ± 0.0005	0.54 ± 0.009	0.091 ± 0.02