. 2012 Feb 3;17(2):1388–1407. doi: 10.3390/molecules17021388

Table 1.

Series (6a–f and 7a–f) obtained through Michael addition reaction between arylpiperazines and benzo[b]thiophenpropenone 5a,b.

Entry	Y	X	R	Yield (%)	m.p (°C)	Entry	Y	X	R	Yield (%)	m.p (°C)
6a	CH	H	OMe	88	169–170	7a	CH	H	H	59	….. ^a
6b	CH	2-F	OMe	66	134–135	7b	CH	2-F	H	90	….. ^b
6c	CH	4-F	OMe	60	131–132	7c	CH	4-F	H	38	117–118
6d	CH	2-OMe	OMe	67	128–129	7d	CH	2-OMe	H	50	45–47
6e	N	H	OMe	60	174–175	7e	N	H	H	71	56–58
6f	CH	4-NO₂	OMe	65	161–162	7f	CH	4-NO₂	H	69	138–141

^a,b yellow oils.