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Displayed interactions in the binding site.
| Residues 5-HT1AR | Ligands | |||
|---|---|---|---|---|
| 6d | 6f | 7f | 7e | |
| D116 | + | + | + | +, ¥ |
| F360 | Y | Y | Y | Ya |
| F361 | Y | - | - | NOI |
| L380 | NOI | - | - | + |
| N385 | NOI | |||
+: H-bonding; Y: Hydrophobic interactions; Ya: Edge-to-face interactions; -: Repulsive interactions; ¥: electrostatic interactions; NOI, no observed interactions.
