Table 5.
Effect of quercetin on myocardium TBARS, GSH levels and SOD, CAT, GSH-Px activities in ISO rats.
| Group | TBARS (nmol/g of tissue) | GSH (nmol/mg protein) | SOD (U/mg protein) | CAT (U/mg protein) | GSH-Px (U/mg protein) |
|---|---|---|---|---|---|
| Normal control | 4.17 ± 0.31 | 69.25 ± 2.99 | 267.28 ± 11.73 | 49.14 ± 1.54 | 68.14 ± 4.02 |
| ISO control | 8.41 ± 0.47 b | 32.16 ± 1.42 b | 98.27 ± 4.29 b | 18.23 ± 0.95 b | 32.07 ± 1.32 b |
| ISO + quercetin (50 mg/kg b.w.) | 6.94 ± 0.23 d | 41.07 ± 2.07 d | 153.28 ±14.02 d | 26.07 ± 1.44 d | 45.18 ± 2.05 d |
| ISO + quercetin (100 mg/kg b.w.) | 6.03 ± 0.29 d | 53.24 ± 3.01 d | 197.04 ± 12.16 d | 35.19 ± 1.53 d | 57.02 ± 2.51 d |
| ISO + quercetin (150 mg/kg b.w.) | 5.26 ± 0.19 d | 66.93 ± 2.18 d | 241.71 ± 18.02 d | 48.01 ± 2.97 d | 66.32 ± 3.13 d |
b P < 0.01, compared with normal control group; d P < 0.01, compared with ISO control group.