Table 1.
1H-NMR (400 Hz) and 13C-NMR (100 Hz) spectral data of neonaucline (1) and cadamine (2) in CDCl3.
| Position | 1H (δH, Hz) (1) | 13C (δC, CDCl3) | 1H (δH, Hz) (2) | 13C(δC,CDCl3) |
|---|---|---|---|---|
| N-H | 8.72s | - | 7.95s | - |
| 2 | - | 127.4 | - | 134.9 |
| 3 | - | 138.2 | 4.43m | 46.3 |
| 5 | 4.54t (2H,6.8) | 40.7 | 2.94, 3.22m | 47.6 |
| 6 | 3.19t (2H,6.8) | 19.4 | 2.80, 2.98m | 21.9 |
| 7 | - | 116.9 | - | 107.9 |
| 8 | - | 125.7 | - | 126.9 |
| 9 | 7.64d (7.8) | 119.9 | 7.48 d (8.0) | 118.3 |
| 10 | 7.18dd (7.8,7.8) | 120.9 | 7.10 dd (8.0,8.0) | 119.4 |
| 11 | 7.35dd (7.8,7.8) | 125.6 | 7.16 dd (8.0,8.0) | 121.9 |
| 12 | 7.46d (7.8) | 111.9 | 7.27 d (8.0) | 111.1 |
| 13 | - | 138.6 | - | 136.2 |
| 14 | 7.88 s | 95.1 | 3.25,3.51 m | 28.3 |
| 15 | - | 141.9 | - | 124.5 |
| 16 | - | 117.8 | - | 130.8 |
| 17 | 9.32 s | 155.4 | 8.51 s | 151.8 |
| 19 | 9.69 s | 154.2 | 8.96 s | 150.0 |
| 20 | 120.4 | - | 144.8 | |
| 21 | - | 166.4 | - | 166.3 |
| 22-OMe | 4.00 s | 52.5 | 3.88 s | 52.4 |
| 23 | - | 166.4 | 4.10 m | 62.6 |
| 24 | - | - | 3.61, 3.75 m | 63.6 |