Table 2.
Mean steady state reaction rates of 7 mol % Eu(OTf)3 (a) or 7 mol % Eu(NO3)3 (b) catalyzed Mukaiyama aldol reactions. Error represents standard error of the mean of 3 independent samples.
| (a) | (b) | |||
|---|---|---|---|---|
| % H2O in THF (v/v) | steady state reaction rate (μM s–1) | % H2O in THF (v/v) | steady state reaction rate (μM s–1) | |
| 0 | 0.29 ± 0.06 | 0 | nd | |
| 1 | 0.33 ± 0.03 | 1 | 0.008 ± 0.001 | |
| 5 | 1.0 ± 0.2 | 5 | 0.11 ± 0.02 | |
| 10 | 1.4 ± 0.2 | 10 | 0.33 ± 0.06 | |
| 15 | 1.5 ± 0.2 | 15 | 0.48 ± 0.04 | |
| 20 | nd | 20 | nd | |
| 25 | 1.45 ± 0.08 | 25 | 1.0 ± 0.2 | |
| 30 | nd | 30 | nd | |
| 40 | 1.3 ± 0.1 | 40 | 1.3 ± 0.2 |
nd = not determined.