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. 2012 Oct 22;17(10):12449–12459. doi: 10.3390/molecules171012449

Figure 2.

Figure 2

(a) Histological section of gastric mucosa in a rat pre-treated with 10 ml/kg of 10% Tween-20 (ulcer control) only. There is severe disruption to the surface epithelium, and edema of the submucosal layer with leucocyte infiltration. (b) Histological section of gastric mucosa in a rat pre-treated with 10 ml/kg of Cimetidine (50 mg/kg). There is mild disruption to the surface epithelium with mild edema and leucocytes infiltration of the submucosal layer. (c) Histological section of gastric mucosa in a rat pre-treated with 10 ml/kg of TNS (60 mg/kg). There is no disruption to the surface epithelium with no edema and no leucocytes infiltration of the submucosal layer.