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. 2012 Aug 24;17(9):10052–10064. doi: 10.3390/molecules170910052

Figure 3.

Figure 3

The effect of formononetin on IL-1β-induced NO formation and apoptotic pathway in INS-1 cells. Cells were treated with the indicated concentrations of IL-1β and formononetin for 24h. (A) The level of NO in medium of INS-1 cells was determined using Griess method. Values are the means ± SD (n = 3) of three individual experiments. * p < 0.05, ** p < 0.01 vs. ctr (DMSO); # p < 0.05, ## p < 0.01 vs. group treated with IL-1β excluding formononetin. (B) The expression of apoptotic genes were analyzed by western blot in INS-1 cells.