Table 1.
Differentially expressed genes in HBEC exposed to PM2.5 versus control.
| Probe Set ID | RefSeq ID | Gene Symbol | p-value | Fold Change | Regulation |
|---|---|---|---|---|---|
| 203665_at | NM_002133 | HMOX1 | 0.0045 | 24.58 | up |
| 209921_at | NM_014331 | SLC7A11 | 0.0004 | 10.45 | up |
| 202436_s_at | NM_000104 | CYP1B1 | 0.0015 | 7.02 | up |
| 201266_at | NM_003330 | TXNRD1 | 0.0014 | 6.96 | up |
| 205749_at | NM_000499 | CYP1A1 | 0.0185 | 5.54 | up |
| 203925_at | NM_002061 | GCLM | 0.0006 | 3.71 | up |
| 202923_s_at | NM_001498 | GCLC | 0.0110 | 3.29 | up |
| 201468_s_at | NM_000903 | NQO1 | 0.0139 | 2.92 | up |
| 204151_x_at | NM_001353 | AKR1C1 | 0.0042 | 2.91 | up |
| 206172_at | NM_000640 | IL13RA2 | 0.0110 | 2.72 | up |
| 211653_x_at | NM_001354 | AKR1C2 | 0.0083 | 2.70 | up |
| 209387_s_at | NM_014220 | TM4SF1 | 0.0472 | 2.47 | up |
| 210845_s_at | NM_002659 | PLAUR | 0.0104 | 2.18 | up |
| 206683_at | NM_003447 | ZNF165 | 0.0090 | 2.14 | up |
| 212907_at | NM_021194 | SLC30A1 | 0.0357 | 2.14 | up |
| 214211_at | NM_002032 | FTH1 | 0.0270 | 2.08 | up |
| 208963_x_at | NM_013402 | FADS1 | 0.0202 | 2.03 | up |
| 205767_at | NM_001432 | EREG | 0.0160 | 1.98 | up |
| 219475_at | NM_182981 | OSGIN1 | 0.0103 | 1.98 | up |
| 207675_x_at | NM_057091 | ARTN | 0.0313 | 1.97 | up |
| 202842_s_at | NM_012328 | DNAJB9 | 0.0309 | 1.96 | up |
| 202266_at | NM_016614 | TDP2 | 0.0001 | 1.95 | up |
| 201625_s_at | NM_005542 | INSIG1 | 0.0446 | 1.93 | up |
| 209882_at | NM_006912 | RIT1 | 0.0114 | 1.93 | up |
| 201489_at | NM_005729 | PPIF | 0.0093 | 1.92 | up |
| 213112_s_at | NM_003900 | SQSTM1 | 0.0191 | 1.91 | up |
| 204420_at | NM_005438 | FOSL1 | 0.0323 | 1.80 | up |
| 202284_s_at | NM_000389 | CDKN1A | 0.0324 | 1.77 | up |
| 206907_at | NM_003811 | TNFSF9 | 0.0032 | 1.74 | up |
| 219697_at | NM_006043 | HS3ST2 | 0.0291 | 1.72 | up |
| 204970_s_at | NM_002359 | MAFG | 0.0032 | 1.69 | up |
| 213187_x_at | NM_000146 | FTL | 0.0471 | 1.68 | up |
| 212717_at | NM_014798 | PLEKHM1 | 0.0319 | 1.66 | up |
| 206498_at | NM_000275 | OCA2 | 0.0221 | 1.66 | up |
| 202672_s_at | NM_001674 | ATF3 | 0.0041 | 1.57 | up |
| 202021_x_at | NM_005801 | EIF1 | 0.0460 | 1.55 | up |
| 202067_s_at | NM_000527 | LDLR | 0.0128 | 1.54 | up |
| 204958_at | NM_004073 | PLK3 | 0.0153 | 1.50 | up |
| 202207_at | NM_005737 | ARL4C | 0.0139 | 3.24 | down |
| 202887_s_at | NM_019058 | DDIT4 | 0.0123 | 2.66 | down |
| 201890_at | NM_001034 | RRM2 | 0.0097 | 2.26 | down |
| 211450_s_at | NM_000179 | MSH6 | 0.0486 | 2.26 | down |
| 201849_at | NM_004052 | BNIP3 | 0.0293 | 2.20 | down |
| 219250_s_at | NM_013281 | FLRT3 | 0.0425 | 2.10 | down |
| 209120_at | NM_021005 | NR2F2 | 0.0056 | 2.01 | down |
| 202464_s_at | NM_004566 | PFKFB3 | 0.0289 | 1.99 | down |
| 208808_s_at | NM_002129 | HMGB2 | 0.0462 | 1.99 | down |
| 203344_s_at | NM_002894 | RBBP8 | 0.0280 | 1.97 | down |
| 218718_at | NM_016205 | PDGFC | 0.0044 | 1.97 | down |
| 207173_x_at | NM_001797 | CDH11 | 0.0432 | 1.95 | down |
| 201669_s_at | NM_002356 | MARCKS | 0.0448 | 1.92 | down |
| 207826_s_at | NM_002167 | ID3 | 0.0285 | 1.84 | down |
| 204967_at | NM_001649 | SHROOM2 | 0.0141 | 1.80 | down |
| 202628_s_at | NM_000602 | SERPINE1 | 0.0486 | 1.77 | down |
| 212599_at | NM_015570 | AUTS2 | 0.0053 | 1.77 | down |
| 203274_at | NM_012151 | F8A1 | 0.0118 | 1.76 | down |
| 208673_s_at | NM_003017 | SRSF3 | 0.0188 | 1.76 | down |
| 203476_at | NM_006670 | TPBG | 0.0400 | 1.75 | down |
| 209189_at | NM_005252 | FOS | 0.0366 | 1.72 | down |
| 209784_s_at | NM_002226 | JAG2 | 0.0032 | 1.70 | down |
| 203625_x_at | NM_005983 | SKP2 | 0.0040 | 1.70 | down |
| 222036_s_at | NM_005914 | MCM4 | 0.0439 | 1.66 | down |
| 202219_at | NM_005629 | SLC6A8 | 0.0253 | 1.65 | down |
| 205449_at | NM_013299 | SAC3D1 | 0.0328 | 1.65 | down |
| 212168_at | NM_006047 | RBM12 | 0.0031 | 1.64 | down |
| 209286_at | NM_006449 | CDC42EP3 | 0.0060 | 1.63 | down |
| 204334_at | NM_003709 | KLF7 | 0.0105 | 1.63 | down |
| 208579_x_at | NM_017445 | H2BFS | 0.0173 | 1.62 | down |
| 204069_at | NM_002398 | MEIS1 | 0.0281 | 1.60 | down |
| 203797_at | NM_003385 | VSNL1 | 0.0172 | 1.58 | down |
| 203764_at | NM_014750 | DLGAP5 | 0.0181 | 1.58 | down |
| 213051_at | NM_020119 | ZC3HAV1 | 0.0104 | 1.58 | down |
| 208051_s_at | NM_006451 | PAIP1 | 0.0321 | 1.57 | down |
| 203405_at | NM_003720 | PSMG1 | 0.0304 | 1.57 | down |
| 211744_s_at | NM_001779 | CD58 | 0.0273 | 1.57 | down |
| 206277_at | NM_002564 | P2RY2 | 0.0179 | 1.56 | down |
| 204715_at | NM_015368 | PANX1 | 0.0375 | 1.56 | down |
| 201312_s_at | NM_003022 | SH3BGRL | 0.0383 | 1.55 | down |
| 213088_s_at | NM_015190 | DNAJC9 | 0.0253 | 1.55 | down |
| 203803_at | NM_016297 | PCYOX1 | 0.0350 | 1.54 | down |
| 201624_at | NM_001349 | DARS | 0.0225 | 1.54 | down |
| 214214_s_at | NM_001212 | C1QBP | 0.0468 | 1.54 | down |
| 212320_at | NM_178014 | TUBB | 0.0185 | 1.53 | down |
| 208405_s_at | NM_006016 | CD164 | 0.0465 | 1.51 | down |
| 213019_at | NM_012416 | RANBP6 | 0.0002 | 1.51 | down |
| 212922_s_at | NM_020197 | SMYD2 | 0.0002 | 1.50 | down |
| 209025_s_at | NM_006372 | SYNCRIP | 0.0481 | 1.50 | down |
| 201163_s_at | NM_001553 | IGFBP7 | 0.0458 | 1.50 | down |
| 214800_x_at | NM_001207 | BTF3 | 0.0036 | 1.50 | down |