Table 1.
Day | Control | CEE 800 mg/kg | B[a]P 200 mg/kg | CEE + B[a]P 200 + 200 mg/kg | CEE + B[a]P 400 + 200 mg/kg | CEE + B[a]P 800 + 200 mg/kg |
---|---|---|---|---|---|---|
Treatment period | ||||||
0 | 23.39 ± 2.59 | 23.59 ± 1.29 | 23.29 ± 0.68 | 23.12 ± 0.83 | 23.62 ± 0.68 | 23.32 ± 1.50 |
1 | 25.55 ± 2.32 | 24.65 ± 1.93 | 24.75 ± 1.03 | 24.05 ± 0.72 | 24.05 ± 1.35 | 24.75 ± 0.84 |
2 | 26.05 ± 2.46 | 26.80 ± 1.79 | 25.66 ± 0.99 | 26.02 ± 0.71 | 25.99 ± 1.43 | 25.26 ± 0.82 |
3 | 26.79 ± 1.71 | 26.29 ± 1.99 | 26.66 ± 1.10 | 26.71 ± 0.86 | 26.29 ± 0.19 | 26.29 ± 0.38 |
4 | 27.02 ± 2.02 | 27.52 ± 1.94 | 27.02 ± 0.96 | 27.33 ± 0.87 | 27.41 ± 1.34 | 27.13 ± 0.63 |
5 | 27.14 ± 2.22 | 27.84 ± 1.96 | 27.91 ± 0.92 | 28.21 ± 1.33 | 27.91 ± 0.15 | 27.13 ± 0.63 |
6 | 28.69 ± 2.57 | 28.41 ± 1.80 | 29.70 ± 0.83 | 29.21 ± 1.07 | 29.21 ± 1.47 | 29.11 ± 0.16 |
7 | 29.21 ± 2.50 | 29.51 ± 1.84 | 30.83 ± 1.40 | 30.59 ± 0.37 | 29.33 ± 1.39 | 29.98 ± 0.20 |
8 | 29.98 ± 2.48 | 29.51 ± 1.88 | 31.99 ± 1.33 a | 31.23 ± 1.69 | 31.23 ± 1.11 | 30.02 ± 0.20 |
Recovery period | ||||||
9 | 30.59 ± 2.82 | 30.78 ± 2.13 | 32.79 ± 1.51 a | 32.59 ± 1.54 a | 31.23 ± 1.11 | 30.83 ± 0.10 b |
10 | 31.69 ± 3.02 | 31.89 ± 2.83 | 33.13 ± 0.60 a | 32.79 ± 0.86 | 33.03 ± 1.25 | 31.89 ± 1.18 |
11 | 32.89 ± 3.10 | 32.33 ± 2.83 | 33.23 ± 1.26 | 33.63 ± 0.16 | 33.11 ± 1.15 | 32.40 ± 0.11 |
12 | 34.93 ± 3.10 | 34.79 ± 2.83 | 35.20 ± 0.26 | 35.02 ± 0.36 | 34.12 ± 1.05 | 34.50 ± 0.74 |
13 | 34.93 ± 3.14 | 35.20 ± 2.53 | 35.12 ± 1.16 | 35.50 ± 0.60 | 35.20 ± 0.21 | 34.50 ± 0.74 |
14 | 36.13 ± 3.25 | 35.93 ± 2.34 | 36.02 ± 1.21 | 36.02 ± 0.19 | 35.50 ± 0.12 | 35.93 ± 1.80 |
The weight of each mouse was determined daily during the all experiment; The data are average values for 6 animals/group; The letters show significant statistical differences as follows: a with respect to the control value, and b with respect to value in group treated with B[a]P. Analysis of variance and Tukey-Kramer tests (a ≤ 0.05).