Table 1.
Test Extracts and Compounds | Inhibitory Rate for Different Cancer Cell Lines (%, mean ± SD) a | ||||
---|---|---|---|---|---|
MGC-803 b | Bcap-37 c | MCF-7 c | PC3 d | NIH3T3 e | |
Petroleum ether extract f | 14.3 ± 9.1 | 43.1 ± 6.1 | 33.2 ± 1.1 | 27.1 ± 5.2 | 2.6 ± 12.4 |
Ethyl acetate extract f | 94.1 ± 2.8 | 76.4 ± 4.6 | 80.4 ± 2.9 | 86.2 ± 2.1 | 36.5 ± 7.3 |
Methanol extract f | 51.2 ± 2.1 | 51.6 ± 5.1 | 50.0 ± 2.1 | 65.7 ± 7.8 | 69.9 ± 4.8 |
ADM g | 92.1 ± 1.3 | 92.1 ± 1.1 | 91.1 ± 2.2 | 93.4 ± 2.6 | 99.4 ± 0.4 |
Quercetin (3) h | 19.2 ± 2.8 | 41.3 ± 2.9 | 43.5 ± 6.3 | 21.8 ± 8.9 | 5.8 ± 7.7 |
Kampferol (4) | 58.2 ± 3.0 | 51.2 ± 8.1 | 39.2 ± 6.8 | 46.1 ± 5.9 | 11.1 ± 6.7 |
Ursolic acid (7) | 51.7 ± 5.6 | 48.4 ± 5.9 | 49.4 ± 4.1 | 57.7 ±1.9 | 21.7 ± 4.9 |
Betulin (8) | 43.7 ± 6.7 | 53.2 ± 3.2 | 53.2 ± 5.4 | 17.3 ± 5.2 | 33.5 ± 7.1 |
Betulonic acid (9) | 68.1 ± 2.6 | 44.9 ± 2.9 | 56.1 ± 4.4 | 52.4 ± 4.2 | 22.1 ± 6.2 |
Betulone (10) | 52.2 ± 5.3 | 54.2 ± 2.2 | 64.7 ± 7.3 | 52.3 ± 3.3 | 36.3 ± 7.1 |
Tectoridin (11) | 12.6 ± 2.6 | 17.3 ± 4.2 | 10.0 ± 7.9 | 18.2 ± 6.2 | 5.9 ± 5.2 |
Irisflorentin (12) | 29.4 ± 4.9 | 17.0 ± 9.8 | 39.1 ± 5.0 | 34.0 ± 4.8 | 25.0 ± 8.1 |
4′,5,6-Trihydroxy-7-methoxyisoflavone (13) | 13.4 ± 7.5 | 12.9 ± 4.8 | 20.9 ± 8.8 | 14.9 ± 2.0 | 1.7 ± 1.7 |
Tectorigenin (14) | 22.6 ± 3.3 | 18.7 ± 5.4 | 23.7 ± 4.9 | 28.1 ± 4.8 | 18.4 ± 6.1 |
Irilins A (15) | 13.4 ± 7.5 | 12.7 ± 5.1 | 10.4 ± 3.5 | 19.3 ± 4.3 | 9.0 ± 4.8 |
Iridin (16) | 12.4 ± 2.7 | 21.8 ± 3.6 | 11.8 ± 5.2 | 22.7 ± 5.2 | 12.4 ± 7.3 |
Irigenin (17) | 25.6 ± 5.3 | 20.1 ± 7.2 | 25.1 ± 1.2 | 25.7 ± 2.2 | 15.3 ± 1.8 |
Iristectongenin A (18) | 26.6 ± 4.9 | 22.1 ± 8.2 | 19.1 ± 7.2 | 25.7 ± 2.2 | 5.2 ± 6.9 |
Note: a Inhibitory percentage of cells treated with 20 μmol/L of each compound for 72 h and SD = standard deviation; b Stomach cancer; c Breast cancer; d Prostate cancer; e Mouse Fibroblasts; f Inhibitory percentage of cells treated with 50 μg/mL of each extract for 72 h; g The standard compound used for comparison of activities; h Inhibitory percentage of cells treated with 20 µmol/L of each compound for 72 h.