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. 2012 Sep 13;17(9):11026–11045. doi: 10.3390/molecules170911026

Table 1.

Equivalents of coupling reagents used for PNA-PEO solution coupling and degree of amine conversion obtained.

Eq. ratio HATU/DMAP % of amine modification Eq. ratio PyOxim:TEA % of amine modification
1 0 10:2 0
10 44 10:10 33
30 90 10:20 52.1
36 100 20:20 72.3
40:30 100