Table 4.

The relative organ weight per 100 g body weight recorded at the end of the study from male and female rats treated with C. papaya extract measured during the 28 days sub-acute toxicity study.

Sex	Organ	Study Groups
		Control	0.01 g/kg BW	0.14 g/kg BW	2 g/kg BW
Male	Lung	0.52 ± 0.14	0.48 ± 0.11	0.44 ± 0.05	0.49 ± 0.02
	Heart	0.34 ± 0.03	0.33 ± 0.03	0.34 ± 0.00	0.32 ± 0.02
	Liver	4.07 ± 0.36	3.56 ± 0.36	3.97 ± 0.28	3.78 ± 0.22
	Stomach	0.53 ± 0.06	0.51 ± 0.05	0.53 ± 0.05	0.53 ± 0.02
	Spleen	0.21 ± 0.05	0.12 ± 0.02	0.19 ± 0.03	0.22 ± 0.03
	GIT	0.56 ± 0.16	0.44 ± 0.06	0.45 ± 0.18	0.55 ± 0.09
	Kidney Left	0.38 ± 0.04	0.38 ± 0.05	0.39 ± 0.03	0.40 ± 0.05
	Kidney Right	0.38 ± 0.03	0.38 ± 0.04	0.40 ± 0.03	0.41 ± 0.04
	Testis Left	0.39 ± 0.16	0.49 ± 0.07	0.50 ± 0.04	0.52 ± 0.06
	Testis Right	0.42 ± 0.18	0.50 ± 0.07	0.50 ± 0.04	0.53 ± 0.04
	Adrenal Left	0.01 ± 0.01	0.01 ± 0.00	0.01 ± 0.00	0.01 ± 0.01
	Adrenal Right	0.01 ± 0.01	0.01 ± 0.01	0.01 ± 0.01	0.01 ± 0.00
Female	Lung	0.50 ± 0.04	0.49 ± 0.05	0.49 ± 0.05	0.46 ± 0.07
	Heart	0.37 ± 0.04	0.34 ± 0.01	0.35 ± 0.03	0.33 ± 0.03
	Liver	4.02 ± 0.21	3.87 ± 0.18	4.04 ± 0.24	3.85 ± 0.27
	Stomach	0.64 ± 0.09	0.54 ± 0.04	0.58 ± 0.10	0.56 ± 0.06
	Spleen	0.23 ± 0.02	0.21 ± 0.02	0.20 ± 0.02	0.22 ± 0.03
	GIT	0.67 ± 0.12	0.60 ± 0.13	0.61 ± 0.07	0.61 ± 0.09
	Kidney Left	0.37 ± 0.02	0.40 ± 0.01	0.39 ± 0.04	0.39 ± 0.03
	Kidney Right	0.39 ± 0.02	0.40 ± 0.03	0.39 ± 0.04	0.39 ± 0.03
	Ovary Left	0.02 ± 0.01	0.03 ± 0.01	0.03 ± 0.01	0.03 ± 0.02
	Ovary Right	0.02 ± 0.01	0.03 ± 0.01	0.03 ± 0.01	0.03 ± 0.01
	Adrenal Left	0.01 ± 0.00	0.01 ± 0.01	0.02 ± 0.00	0.01 ± 0.01
	Adrenal Right	0.01 ± 0.00	0.01 ± 0.01	0.01 ± 0.00	0.01 ± 0.00
	Urinary bladder	0.04 ± 0.01	0.03 ± 0.01	0.03 ± 0.01	0.03 ± 0.01

Values are expressed as mean ± standard deviation. * p value less than 0.05, (p < 0.05) significant value.