Table 1.

Design program and experimental results of RSM.

Exp. number	Heating Time	Enzyme quantity	Temperature	Extraction yield
	/X1(h)	/X2 (mL)	/X3(°C)	/(mg/g)
1	7.78	43.31	77.8	6.96
2	7.78	43.31	42.16	6.94
3	7.78	23.69	77.8	7.17
4	7.78	23.69	42.16	7.25
5	4.22	43.31	77.8	7.08
6	4.22	43.31	42.16	7.04
7	4.22	23.69	77.8	7.01
8	4.22	23.69	42.16	7.19
9	9	33.5	60	7.11
10	3	33.5	60	7.01
11	6	50	60	7.13
12	6	17	60	7.31
13	6	33.5	90	7.27
14	6	33.5	30	7.41
15	6	33.5	60	7.63
16	6	33.5	60	7.53
17	6	33.5	60	7.59
18	6	33.5	60	7.65
19	6	33.5	60	7.57
20	6	33.5	60	7.67
R2				0.95
CV (%)				1.02