2 |
4,5 (1H,
m) |
4.70 (1H,
q) |
3.48 (
q, 6; 10) |
4.07 (
q, 6; 10) |
4.08 (1H,
q, 6, 10) |
3.6 (
dd, 6.2, 11) |
4.5 (
m) |
3 |
3.0 (
brd, 10.7) 1.9 (m) |
3.28 (1H,
m) 2.22 (1H) |
|
|
|
3.0 (
dt, 13.1, 4.1) 1.95 (dd, 2.9, 10.7) |
3.0 (
brd, 10.7) 2.05–1.9 (m) |
5 |
3.11 (
td, 9, 3.2) 2.25 (m) |
3.48 (1H,
m) 2.40 (m, 13.8) |
|
|
|
3.1 (
td, 7.6, 2.8) 2.3 (m) |
3.1 (
td, 9, 3.2) 2.25 (m) |
6 |
2.05 (
m) 1.55 (m) |
2.20 (1H,
m) 1.80 (1H, m) |
|
|
|
2.4 (
m) 1.5 (m) |
2.05–1.9 (
m) 1.6–1.35 (m) |
9 |
6.83 (
d, 8.7) |
6.82 (2H, 8.0) |
6.56 (3H,
m) |
6.9 (3H,
m) |
7.17 (3H,
m) |
6.75 (
d, 1.7) |
6.83 (
d, 8.7) |
10 |
7.07 (
t, 8.7) |
7.08 (1H,
d, 8.0) |
6.56 (3H,
m) |
6.9 (3H,
m) |
7.17 (3H,
m) |
|
7.07 (
t, 8.7) |
11 |
6.8 (
d, 8.7) |
6.82 (2H, 8.0) |
6.56 (3H,
m) |
6.9 (3H,
m) |
7.17 (3H,
m) |
6.6 (
dd, 1.7, 7) |
6.8 (
d, 8.7) |
12 |
|
|
|
|
8.13 (1H, ) |
6.7 (
d, 7) |
|
14 |
1.73 (
qt, 13.4) 1.5 (brd, 13) |
2.0 (1H) 1.60 (1H,
m) |
|
|
|
1.8 (
qt, 13.1, 4.0) 1.5 (m) |
1.7 (
qt, 13, 4) 1.6–1.35 (m) |
15 |
1.6 (
m) 1.05 (m) |
3.22 (
m, 14.5, 7.0) |
|
|
|
1.6 (
m) 1.2 (dd, 4.5, 13.4) |
1.6–1.35 (
m) 1.3–1.05 (m) |
16 |
1.95 (
m) 1.35 (m) |
1.30 (1H,
m) 2.04 (1H, m) |
|
|
|
1.6 (
m) 1.4 (dt, 14.0, 3.4) |
2.05–1.9 (
m) 1.6–1.35 (m) |
17 |
2.0 (
m) 1.1 (m) |
1.10 (1H,
dq, 14.7) 2.18 (1H, m) |
|
|
|
2.0 (
dd, 2.6, 12.3) 1.1 (dt, 12.6, 2.5) |
2.05–1.9 (
m) 1.3–1.05 (m) |
18 |
0.6 (
t, 7.1) |
0.63 (3H,
t, 6.9) |
0.6 (3H,
t, 6) |
0.72 (3H,
t) |
0.73 (3H,
t) |
0.7 (
t, 7.3) |
0.6 (
t, 7) |
19 |
1.2 (
dq, 14, 7.1) 0.8 (dq, 14, 7.1) |
0.75 (1H,
q, 6.9) 1.22 (1H, m) |
|
|
|
1.5 (
m) 0.9 (dq, 14.3, 7.3) |
1.3–1.05 (
m) 0.8 (dq, 14, 7) |
21 |
2.23 (1H,
s) |
2.20 (1H,
s) |
2.16 (1H,
s) |
2.28 (1H,
s) |
|
2.2 (1H,
s) |
2.2 (
s) |
10-OCH3 |
|
|
|
|
|
3.8 (3H,
s) |
|
12-OCH3 |
3.87 (3H,
s) |
3.90 (3H,
s) |
3.78 (3H,
s) |
|
|
|
3.87 (
s) |
15-OCH3 |
|
3.33 (3H,
s) |
|
|
|
|
|
COCH3 |
2.2 (3H,
s) |
2.22 (3H,
s) |
- |
2.32 (3H,
s) |
2.27 (3H,
s) |
|
|
COCH2CH3 |
|
|
|
|
|
|
2.6 (
dq, 13, 6.5) 2.4 (m) |
COCH2CH3 |
|
|
|
|
|
|
1.3 (
t, 6.5) |
OH |
|
|
|
10.83 (
s) |
|
|
|
NH |
|
|
3.35 (1H,
s) |
|
|
|
|