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. 2012 Sep 13;17(9):11067–11078. doi: 10.3390/molecules170911067

Table 3.

Particle size (x10, x90 [nm]) of APIs IIII and concentration [%] of macrogol 6000 in dichloromethane (DCM) or acetone (AC). All the presented results are reported as medium value of four independent measurements, repeatability was up to 6%. Samples that contained nanoparticles <200 nm are bolded; nanoparticles <10 nm are indicated by grey background. (S.No. = sample number).

API/Solvent Macrogol 6000
S.No. 1% S.No. 3% S.No. 5% S.No. 10%
x10 x90 x10 x90 x10 x90 x10 x90 Particle size [nm]
I/DCM 49 534 773 50 15 16.86 51 179 247 52 1 2
I/AC 53 2 2 54 3 4 55 2 3 56 193 292
II/DCM 57 90 99 58 408 576.85 59 197 285 60 211 279
II/AC 61 1 2 62 1 2.27 63 1 2 64 29 44
III/DCM 65 3 4 66 2 3 67 27 30 68 1 1
III/AC 69 2929 3222 70 3 3 71 90 99 72 6 6