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. 2012 Sep 13;17(9):11067–11078. doi: 10.3390/molecules170911067

Table 4.

Particle size (x10, x90 [nm]) of APIs IIII and concentration [%] of sodium carboxymethyl cellulose in dichloromethane (DCM) or acetone (AC). All the presented results are reported as medium value of four independent measurements, repeatability was up to 6%. Samples that contained nanoparticles <200 nm are bolded; nanoparticles <10 nm are indicated by grey background. (S.No. = sample number).

API/Solvent Sodium carboxymethyl cellulose
S.No. 1% S.No. 3% S.No. 5% S.No. 10%
x10 x90 x10 x90 x10 x90 x10 x90 Particle size [nm]
I/DCM 73 101 111 74 2 3 75 1 1 76 1 2
I/AC 77 6 9 78 357 486 79 7 9 80 2 3
II/DCM 81 90 99 82 1 2 83 3 3 84 879 1249
II/AC 85 2 3 86 90 99 87 1 2 88 101 111
III/DCM 89 1 2 90 8799 9987 91 1 2 92 534 731
III/AC 93 4 6 94 9345 10,281 95 9345 10,281 96 2 2