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. 2012 Sep 13;17(9):11067–11078. doi: 10.3390/molecules170911067

Table 5.

Particle size (x10, x90 [nm]) of APIs IIII and concentration [%] of sodium carboxymethyl dextran in dichloromethane (DCM) or acetone (AC). All the presented results are reported as medium value of four independent measurements, repeatability was up to 6%. Samples Samples that contained nanoparticles <200 nm are bolded; nanoparticles <10 nm are indicated by grey background. (S.No. = sample number).

API/Solvent Sodium carboxymethyl dextran
S.No. 1% S.No. 3% S.No. 5% S.No. 10%
x10 x90 x10 x90 x10 x90 x10 x90 Particle size [nm]
I/DCM 97 5862 8981 98 1 1 99 20 31 100 17 26
I/AC 101 1 1 102 8 9 103 3 4 104 90 99
II/DCM 105 209 275 106 354 422 107 9345 10,281 108 2022 3205
II/AC 109 3 3 110 9345 10,281 111 535 729 112 1 2
III/DCM 113 1 1 114 1 2 115 1418 1560 116 3 5
III/AC 117 9344 10,281 118 101 111 119 5 8 120 22 24