Table 6.
View of formed samples of nanoparticles (≤900 nm) depending on solvents and type and amount of excipients. (conc. = concentration, excp. = excipient, dichloromethane = DCM, acetone = AC, Tween 80 = TW, sodium dodecyl sulfate = SDS, macrogol 6000 = PEG, sodium carboxymethyl cellulose = SCMC, sodium carboxymethyl dextran = SCMD).
| Excp. conc./type | DCM | Sum total | Overall average x90[nm] | AC | Sum total | Overall average x90[nm] | ||||||
| 1% | 3% | 5% | 10% | 1% | 3% | 5% | 10% | |||||
| number of nanop. samples | number of nanop. samples | |||||||||||
| TW | 3 | 2 | 2 | 3 | 10 | 149 | 2 | 2 | 1 | 3 | 8 | 72 |
| SDS | 2 | 3 | 3 | 3 | 11 | 90 | 2 | 3 | 3 | 2 | 10 | 106 |
| PEG | 3 | 3 | 3 | 3 | 12 | 193 | 2 | 3 | 3 | 3 | 11 | 42 |
| SCMC | 3 | 2 | 3 | 2 | 10 | 96 | 3 | 2 | 2 | 3 | 10 | 73 |
| SCMD | 2 | 3 | 1 | 2 | 8 | 95 | 2 | 2 | 3 | 3 | 10 | 99 |
| Sum total | 13 | 13 | 12 | 13 | 51 | 623 | 11 | 12 | 12 | 14 | 49 | 392 |
| Overall average | 136 | 123 | 106 | 145 | 510 | 125 | 104 | 68 | 103 | 45 | 320 | 78 |
| 127 | 80 | |||||||||||