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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Neuropharmacology. 2018 Oct 3;143:289–298. doi: 10.1016/j.neuropharm.2018.10.002

Figure 6.

Figure 6.

Mediating effect of post-extinction AMYG-HPC RS-FC on the link between pre-extinction THC administration and next-day extinction recall, as measured via US expectancy ratings to the CS+E. Path a, significant impact of THC on AMYG-HPC RSFC; Path b, significant correlation of AMYG-HPC RS-FC and next-day CS+E expectancy ratings; Path a*b, significant indirect impact of THC on next-day CS+E expectancy ratings; Path c, non-significant direct impact of THC on next-day CS+E expectancy ratings. THC, Δ9-tetrahydrocannabinol; PBO, placebo; AMYG, amygdala; HPC, hippocampus; CS+E, extinguished conditioned stimulus; US, unconditioned stimulus