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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Neuropharmacology. 2018 Sep 28;143:239–249. doi: 10.1016/j.neuropharm.2018.09.045

Figure 3:

Figure 3:

Male and female TK rats after CIE have distinct responses during CS retrieval. (a) Schematic of CS retrieval protocol. (b-c) Mean (±SE) freezing (change in freezing from baseline) did not differ between treatment groups in males (b) and females (c) during the 3 min context retrieval. (d) Mean (±SE) freezing (change in freezing from baseline) in males show that Valcyte− CIE rats had reduced freezing during CS retrieval during tones 1-4 compared with CIE naïve rats and Valcyte+ CIE rats. *p<0.05 vs. Valcyte− CIE rats; #p<0.05 vs. tone 1. (e) Mean (±SE) freezing (change in freezing from baseline) in females show no significant effect of treatment on CS retrieval during tones 1-3. During tone 4, Valcyte+ CIE rats show reduced freezing compared with CIE naïve rats and Valcyte− CIE rats. *p<0.05 vs. Valcyte+ CIE rats.