Table 2.
Cancer Risks from 99mTc Pyrophosphate Imaging in Women. Assumes 10 mCi dose; for 20 mCi dose one should double these risks.
| Age | Future Risk of Developing Cancer (chances in 100,000) for Women with 90% Uncertainty Range in Parentheses | |||||
|---|---|---|---|---|---|---|
| Bladder | Kidney | Leukemia | Ovary | Total | ||
| 40 | Excess Future Risk from 99mTc-PYP | 8.98 (2.61,20.5) | 0.473 (0.0449,1.27) | 1.57 (0.483,3.48) | 0.522 (0.127,1.30) | 11.5 (4.17,23.6) |
| Baseline Future Risk | 1210 (1170,1250) | 1040 (1010,1080) | 613 (586,641) | 1410 (1370,1450) | 4274 (4131,4419) | |
| % Risk from 99mTc-PYP | 0.74% | 0.05% | 0.26% | 0.04% | 0.27% | |
| 50 | Excess Future Risk from 99mTc-PYP | 8.76 (2.59,19.9) | 0.430 (0.0408,1.15) | 1.60 (0.397,3.74) | 0.458 (0.112,1.14) | 11.3 (3.95,23.0) |
| Baseline Future Risk | 1210 (1170,1240) | 1000 (967,1030) | 585 (560,611) | 1310 (1280,1350) | 4107 (3973,4243) | |
| % Risk from 99mTc-PYP | 0.72% | 0.04% | 0.27% | 0.03% | 0.27% | |
| 60 | Excess Future Risk from 99mTc-PYP | 8.06 (2.5,18.1) | 0.354 (0.0332,0.936) | 1.64 (0.283,4.06) | 0.362 (0.0874,0.891) | 10.4 (3.63,21.0) |
| Baseline Future Risk | 1160 (1130,1200) | 891 (862,921) | 543 (521,567) | 1110 (1080,1150) | 3714 (3596,3836) | |
| % Risk from 99mTc-PYP | 0.69% | 0.04% | 0.30% | 0.03% | 0.28% | |
| 70 | Excess Future Risk from 99mTc-PYP | 6.55 (2.17,14.3) | 0.248 (0.0228,0.633) | 1.56 (0.180,4.16) | 0.253 (0.0595,0.625) | 8.61 (3.18,17.1) |
| Baseline Future Risk | 1010 (985,1040) | 684 (661,707) | 474 (455,493) | 831 (806,856) | 3001 (2907,3097) | |
| % Risk from 99mTc-PYP | 0.64% | 0.04% | 0.33% | 0.03% | 0.29% | |
| 80 | Excess Future Risk from 99mTc-PYP | 4.42 (1.59,9.24) | 0.134 (0.0119,0.322) | 1.18 (0.0944,3.32) | 0.148 (0.0326,0.381) | 5.88 (2.45,11.4) |
| Baseline Future Risk | 737 (716,757) | 401 (386,416) | 355 (341,369) | 519 (502,536) | 2011 (1945,2077) | |
| % Risk from 99mTc-PYP | 0.60% | 0.03% | 0.33% | 0.03% | 0.29% | |