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. 2018 Aug 14;187(12):2705–2715. doi: 10.1093/aje/kwy173

Table 3.

Estimates of 3 Target Parameters Using 2 Approaches to Handle Missing Data in the Example Study of Maternal Mental Illness and Child Behavior, Longitudinal Study of Australian Children (Waves 1–3), 2004–2008

Parameter Estimate (SE) 95% CI Is Estimate Reliablea if We Adopt:
m-DAG E? m-DAG J?
Proportion of mentally ill mothers at wave 1
 Available-case analysis 0.21 (0.01) 0.20, 0.22 No No
 MICE 0.21 (0.01) 0.20, 0.23 No No
Mean SDQ scoreb of children at wave 3
 Available-case analysis 7.48 (0.09) 7.31, 7.65 No No
 MICE 7.74 (0.09) 7.57, 7.90 No No
Regression-adjusted difference in mean SDQ scorec
 Available-case analysis 0.59 (0.20) 0.20, 0.98 Yes No
 MICE 0.64 (0.21) 0.23, 1.06 Yes No

Abbreviations: CI, confidence interval; m-DAG, missingness directed acyclic graph; MICE, multiple imputation by chained equations; SDQ, Strengths and Difficulties Questionnaire; SE, standard error.

a This indicates whether the estimate can be considered reliable according to which m-DAG from Figure 2 is adopted, based on the recoverability of the parameter in that m-DAG.

b Range, 0–40. A higher score indicates increased behavioral difficulties.

c Comparing mentally ill mothers with non–mentally ill mothers.