Figure 2.

PFS based on prior treatment history and cytogenetic risk (ITT population). Subgroup analysis of PFS based on prior lines of therapy, prior treatment exposure, refractoriness to lenalidomide at the last prior line of therapy, treatment-free interval, and cytogenetic risk. Patients with high-risk cytogenetics had any of t(4;14), t(14;16), or del17p cytogenetic abnormalities as determined by central next-generation sequencing. Standard-risk patients had an absence of high-risk abnormalities. PFS: progression-free survival; ITT: intent-to-treat; D-Vd: daratumumab plus bortezomib and dexamethasone; Vd: bortezomib and dexamethasone; CI: confidence interval; NR: not reached.