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. 2018 Dec;103(12):e571–e574. doi: 10.3324/haematol.2018.191718

Figure 2.

Figure 2.

The lymphoid-primed multipotent progenitor cell (LMPP) population displays an MLL-AF4 gene expression signature. (A) Quantitative PCR strategy in fresh fetal liver cells (n = 6-7) and cells derived from primary recipients (n = 3). Quantitative PCR of (B) Flt3, (C) Meis1, (D) Hoxa9, (E) Hmga2, (F) Lmo2, (G) Runx1, (H) Cdk6, (I) Il7r, (J) Pax5, (K) Ikaros, (L) E2a, (M) Bcl-2, (N) Mcl1, (O) Twist1. (P) Early stages of t(4;11) MLL-AF4 infant leukemia based on the pre-leukemia mouse model. A non-parametric Mann-Whitney test was used to compare datasets with a significance cut-off of P<0.05 (*), P<0.01 (**), P<0.001 (***) or P<0.0001(****).