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. 2018 Aug 1;70(6):1685–1695. doi: 10.1007/s10616-018-0245-1

Table 3.

Comparative analysis of different migration assays with respect to pipette tip assay (s-ARU method)

Cell migration methods/techniques/assays Pipette tip assay (s-ARU method) Trans-well migration assay (Boyden chamber) Scratch Assay Electric fence cell migration assay or ECIS Spheroid migration assay Capillary tube assays Time-lapse cell tracking
Cell types supported Adherent and semi-adherent cell cultures Adherent, semi-adherent and non-adherent cell cultures Adherent cell cultures Adherent cell cultures Adherent cell cultures Adherent cell cultures Adherent cell cultures
Measurement Area or diameter Number of cells Area Area Migration area Migration tube distance Cell migration path
Complexity Extremely simple Extremely simple Extremely simple Simple Simple Simple Simple
Cost Low High Low High High High High
References Kramer et al. (2013) and Poujade et al. (2007) Kramer et al. (2013), Liang et al. (2007) and Geback et al. (2009) Kramer et al. (2013) and Cai et al. (2000) Kramer et al. (2013) and Knupfer et al. (2001) Kramer et al. (2013) and Young et al. (1999) Kramer et al. (2013) and Zantl and Horn (2011)