Table 1.
Member | Function | U.S. regulation | Recruitment |
---|---|---|---|
Nonscientific | Voices concerns about potential research subjects and provides a broader community perspective | Protection of Human Subjects (2009): “at least one member whose primary concerns are in nonscientific areas” | Human resources representative, local human rights committee representative |
Nonaffiliated | Unbiased to organization’s financial concerns and represents a community perspective | Protection of Human Subjects (2009): “at least one member who is not otherwise affiliated with the institution and who is not part of the immediate family of a person who is affiliated with the institution” | Can be a local scientist (e.g., physician) or retired professional (e.g., schoolteacher, administrator) who will not have a conflict of interest |
Scientist | Provides expertise on experimental design for research that aligns with that of the organization | Protection of Human Subjects (2009): “at least one member whose primary concerns are in scientific areas” | Local university training program faculty members, relevant research authors aligned with organization’s activity |
Competent experts | Supports projects that require additional expertise outside of that represented by the committee | Protection of Human Subjects (2009): “individuals with competence in special areas to assist in the review of issues which require expertise beyond or in addition to that available on the IRB” | Researchers who have recently published in the relevant area |
IRB Institutional review board