Table 2.
Kruskal-Wallis test of methylation levels in DLGAP2 gene.
| Test | Group | Scores/χ2/p value | Site 1 | Site 2 | Site 3 | Average |
|---|---|---|---|---|---|---|
| KW test | ||||||
| TD | mean score | 57.8 | 62.7 | 58.8 | 57.7 | |
| NTD | 53.0 | 53.3 | 54.7 | 56.2 | ||
| HC | 46.6 | 41.2 | 43.7 | 43.3 | ||
| TD vs NTD vs HC | χ2 | 2.39 | 8.86 | 4.59 | 4.72 | |
| p value | 0.302 | 0.0119 | 0.101 | 0.0945 | ||
| Wilcoxon test | ||||||
| TD vs HC | p value (one-sided) | 0.0716 | 0.0038 | 0.0161 | 0.0225 | |
| p value (two-sided) | 0.143 | 0.0076 | 0.0322 | 0.0450 | ||
| NTD vs HC | p value (one-sided) | 0.17 | 0.0252 | 0.0758 | 0.0409 | |
| p value (two-sided) | 0.34 | 0.0504 | 0.152 | 0.0818 | ||
| TD + NTD vs HC | p value (one-sided) | 0.0828 | 0.0038 | 0.0195 | 0.0153 | |
| p value (two-sided) | 0.1626 | 0.0076 | 0.0389 | 0.0306 | ||
| TD vs NTD | p value (one-sided) | 0.229 | 0.0559 | 0.307 | 0.428 | |
| p value (two-sided) | 0.469 | 0.110 | 0.614 | 0.855 | ||
Abbreviations: TD = schizophrenia patients with tardive dyskinesia (TD), NTD = schizophrenia patients without TD, HC = healthy controls, KW test refers to Kruskal-Wallis test for comparison of 3 groups, mean score is based on the rank, χ2 is based on the chi-square test for the KW test, one sided and two-sided p values are based on the Wilcoxon test for comparison of 2 groups.