Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 30;8:263. doi: 10.1038/s41398-018-0310-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — A Representative images of FDG-PET and CT of a rat brain (sagittal, planar, and coronal section, from left to right). B FDG-PET and CT images that are co-registered with the three-dimensional rat brain atlas. C Major brain regions quantified using the rat brain atlas. 1: Olfactory, 2: Cortex, 3: Basal Ganglia, 4: Septal Area, 5: Corpus Callosum, 6: Hypothalamus, 7: Thalamus, 8: Amygdala, 9: Hippocampus, 10: Midbrain, 11: Cerebellum. D IV Ketamine (10 mg/kg) infusion induced region-specific changes in BGluM as compared with the saline infusion. The IV Ketamine infusion (Scan 1) increased BGluM in the amygdala (E), hippocampus (F), hypothalamus (G), and midbrain (H), whereas decreasing it in the cerebellum (J). The fear memory testing (Scan 2) increased BGluM in the hypothalamus (G) and midbrain (H), whereas decreasing it in the cortex (I). SUV: standard uptake value. The SUV of each region was normalized with the SUV of the whole brain of the same animal. Data are shown as mean ± SEM (*p < 0.05, **p < 0.01 vs. saline controls)