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. 2018 Nov 30;8:17514. doi: 10.1038/s41598-018-35746-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Identification of mXYSR. (A) Schematic representation of the XYSR/mXYSR region. Black bar, black box, white box and arrow indicate the genome, XYSR/mXYSR, LINE-1 element and SOX9/Sox9. Positions are shown with vertical bars and numbers. (B–E) Results of Pipmaker analysis. The centromeric termini of mXYSR (B) and XYSR (C) and the telomeric termini of mXYSR (D) and XYSR (E) are shown. Human and mouse sequences are shown at the top and bottom, respectively. Conserved nucleotides are indicated by dots on the mouse sequence. Hyphens indicate sequences that only exist in the human or mouse. In the non-conserved regions, only the human sequence is shown. Numbers at the top and left are nucleotide positions of query sequences used for the analysis. Horizontal arrows show the area of repetitive sequences. Arrows pointing up and down indicate the positions of edges of XYSR and mXYSR, respectively.