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Effects of Colchicine derivatives (A and B) on MMP decline in both ALL and healthy mitochondria. Colchicine derivatives-induced MMP decline in ALL but not in healthy mitochondria. Columns represent mean of Rhodamine123 fluorescence intensity in ALL and healthy mitochondria treated with colchicine derivatives5-60 min. Values (mean ± S.D.) are from three independent experiments (n = 6). ****p < 0.0001
