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. 2018 Dec 1;7(11):601–608. doi: 10.1302/2046-3758.711.BJR-2018-0075.R2

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© 2018 Author(s) et al.

This is an open-access article distributed under the terms of the Creative Commons Attributions licence (CC-BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, but not for commercial gain, provided the original author and source are credited.

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graphic file with name bonejointres-07-601-g001.jpg — Physical exercise diminished bone loss in ovariectomized (OVX) mice. a) Images of the distal femoral epiphysis and b) quantification of bone volume fraction (BV/TV), trabecular number (Tb.N), and trabecular spacing (Tb.Sp). c) Serum bone markers osteocalcin and CTX-1 were measured by specific enzyme-linked immunosorbent assay (ELISA). *p < 0.05; †p < 0.01. OVX+T, ovariectomized mice that undertook exercise.