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. 2018 Dec 1;7(11):601–608. doi: 10.1302/2046-3758.711.BJR-2018-0075.R2

Table I.

Top diseases and analysis of the functions of differentially expressed genes predicted by Ingenuity Pathway Analysis (IPA)

Top diseases and functions Molecules in network Score
Metabolic disease, inflammatory response, organismal injury and abnormalities ARG1, Bst2, C3, CCL2, Ccl6, Ccl9, CD300LD, Collagen type I, Collagen(s), CREB3L1, CSF2RB, CXCL12, CXCR4, GZMH, ID1, IFIT1B, Ifnar, Ige, IL33, IL12 (complex), IL1R1, IL1RL1, IL1RN, Ly6a (includes others), mir-135, mir-320, MMP9, NFkB (complex), NQO1, OAS2, P38 MAPK, PI3K (complex), PTGS1, RNF213, Wfdc17 47
Metabolic disease, endocrine system disorders, gastrointestinal disease Acp5, AKR1C3, Akt, Alpha catenin, ANTXR2, CCK, COL3A1, CTSK, CTSV, ERK, ERK1/2, F2R, GPNMB, HAS2, HDL-cholesterol, IGFBP7, IRS2, JAK1, Jnk, let-7, LIPA, LPL, p85 (pik3r), PAK1, PDGFRA, PIK3R5, Pka, RGS2, SERPINE1, Tgf beta, THBS4, TNC, TNN, VCAN, XDH 44
Inflammatory response, infectious diseases, cellular movement AHR, CACHD1, CELA1, CLEC12A, COX8A, CXCL6, CYP1B1, EDN1, EMP2, F13A1, FADS3, FOLR2, GADD45A, GBP2, GLIS2, Gpr137bps, GSTM2, IKBKE, IL6, IL10RA, ITGA5, KEAP1, LBP, LTBP2, MGP, mir-32, miR-191 5p, Pcp4l1, PPIF, PTAFR, Rpl29, SASH1, SDC1, TLR3, TNC 20