Figure 4.
Overexpression of miRs in AKT and MAKP phosphorylation. (A) Transfection of miR-19a precursor enhanced AKT phosphorylation; (B) Transfection of miR-23b, 27b precursors overrode the suppressive effects of ERK inhibitors on shear-induced ERK, but not p38 and JNK, activation. Pre-MiR-27b overrode the SP600126 inhibition of JNK phosphorylation under shear. Data are presented as the mean ± SEM (n = 3). * p < 0.05.