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. 2013 Apr 26;18(5):4955–4971. doi: 10.3390/molecules18054955

Figure 5.

Figure 5

Analysis of the enzymatic hydrolysate of NVP-modified DNA, obtained upon reaction of 12-mesyloxy-NVP (6) with salmon testis DNA and subsequent enzymatic hydrolysis to 2'-deoxynucleosides: (a) HPLC-ESI-MS total ion chromatogram; (a1) extracted ion chromatogram and mass spectrum of the m/z 507 ion. Analysis of the reaction mixture obtained upon reaction of 12-mesyloxy-NVP (6) with dT: (b) HPLC-ESI-MS total ion chromatogram; (b1) extracted ion chromatogram and mass spectrum of the m/z 507 ion. Analysis of the synthetic standard, N3-NVP-dT (9): (c) HPLC-ESI-MS total ion chromatogram and mass spectrum of the m/z 507 ion.